As with anything you put on your skin, there is always a chance of a reaction but this can be dramatically reduced by following these steps:

• Patch test the area at least 24 hours prior to using the product
• Refrain from drinking alcoholic products 24 hours before using the product
• Ensure your hands are thoroughly washed both before and after usage
• Shave or remove any excess hair where the product is going to be applied
• Before applying the product make sure your skin is clean, dry and warm
• Creams require a 2-3mm layer over the area whereas gels and sprays can vary
• Cover the area with cling film or plastic wrap making sure its airtight
• You can use masking tape to secure the film in awkward areas
• Leave creams on for no longer than 2 hours whereas gels and sprays activate faster
• Do not apply to anywhere else apart from exterior skin